MATEC Web Conf.
Volume 318, 20207th International Conference of Materials and Manufacturing Engineering (ICMMEN 2020)
|Number of page(s)||6|
|Published online||14 August 2020|
3D-Printed Composite Bone Bricks For Large Bone Tissue Applications
School of Mechanical, Aerospace and Civil Engineering, University of Manchester, Manchester, UK
2 Department of Manufacturing Engineering, Sabanci University, Instabul, Turkey
3 School of Pharmacy and Biomedical Sciences, University of Portsmouth, Portsmouth, UK
* Corresponding author: firstname.lastname@example.org
This study investigates the use of low cost, customizable, biodegradable, polymer-ceramic composite porous structures (bone bricks) for large bone tissue regeneration. Different ceramic materials (hydroxyapatite (HA), β-tri-calcium phosphate (TCP) and Bioglass (45S5) were mixed with poly-ε-caprolactone (PCL). Bone bricks with different material compositions were produced using an extrusion-based additive manufacturing system. Produced bone bricks were morphologically and mechanically assessed. Results allowed to establish a correlation between scaffolds architecture and material composition and scaffolds performance. Reinforced scaffolds showed improved mechanical properties. Best mechanical properties were obtained with PCL/TCP bone bricks and topologies based on 38 double zig zag filaments and 14 spirals.
© The Authors, published by EDP Sciences, 2020
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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