MATEC Web Conf.
Volume 318, 20207th International Conference of Materials and Manufacturing Engineering (ICMMEN 2020)
|Number of page(s)||6|
|Published online||14 August 2020|
Electrospun PCL-Surgihoney meshes for skin wound healing applications
Department of Mechanical, Aerospace and Civil Engineering, University of Manchester, Manchester, UK
* Corresponding author: email@example.com
Skin is a complex and very important tissue, playing a significant protective and regulatory function. It is also prone to a large number of wounds and defects due to external factors such as temperature, chemical agents, and radiation. Accelerating the skin healing process and minimizing the risk of infection is a relevant research challenge. This paper investigates a novel wound dressing based on polycaprolactone (PCL), a synthetic biocompatible and biodegradable polymer, and honey-Surgihoney® (SH). Solution electrospinning was used to produce the wound dressing meshes. Different polymer solutions were prepared by mixing PCL and SH with acetic acid. Human dermal fibroblast were used to assess the biological characteristics of the electrospun meshes. Results show that the presence of SH1 has a positive impact on cell attachment and proliferation.
© The Authors, published by EDP Sciences, 2020
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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