MATEC Web Conf.
Volume 237, 20182018 3rd International Conference on Design, Mechanical and Material Engineering (D2ME 2018)
|Number of page(s)||6|
|Section||Chapter 2: Material Engineering|
|Published online||26 November 2018|
Formulation and Characterization of Topical Anti-acne Spot Gel Containing Herbal Extracts
1 Department of Pharmaceutical Chemistry, College of Pharmacy, Rangsit University, Pathum Thani, Thailand
2 Department of Pharmacognosy, College of Pharmacy, Rangsit University, Pathum Thani, Thailand
This research work aimed to prepare the topical anti-acne spot gel incorporating the crude polyherbal extract that is a traditional Thai herbal recipe, namely “Ya-Sa-Marn-Phlae”. The topical anti-acne spot gels were prepared by add the crude polyherbal extract in each microemulsion or self-microemulsifying system and subsequently mixed in the blank anti-acne spot gel. The pH, viscosity, stability, contamination test, and skin irritation test were evaluated. The topical anti-acne spot gel formulations had a yellowish in color that was visually checked by researcher and photographed by digital camera. They had a pH near to a human skin and good viscosity which ease to use and safe to contact to the skin. They had a good stability and no contamination of Staphylococcus aureus and Escherichia coli. The topical anti-acne spot gels exhibited no oedema formation, and very slight erythema formation. Thus, the topical anti-acne spot gels were safe to apply on the skin without irritation.
© The Authors, published by EDP Sciences, 2018
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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