Influence of 3D printing process parameters and design on mechanical properties of tissue scaffolds

Department of Mechanical and Aerospace Engineering, Brunel University London, UB8 3PH, United Kingdom

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Abstract

This project investigated the influence of printing process parameters on the printability and mechanical properties of bone tissue scaffolds fabricated using fused deposition modelling (FDM). Given that tissue scaffolds require specific structural and mechanical characteristics for their intended applications, the manufacturing process was examined to evaluate the effects of distinct printing parameters on the final scaffold properties. Specimens were fabricated with varying parameter values, assessed for structural integrity, and subjected to uniaxial compression testing to determine their mechanical behaviour. The results revealed that printing parameters significantly influenced both the structural quality and mechanical performance of the scaffolds, notably affecting defect formation, compressive strength, and the Young’s modulus.