| Issue |
MATEC Web Conf.
Volume 197, 2018
The 3rd Annual Applied Science and Engineering Conference (AASEC 2018)
|
|
|---|---|---|
| Article Number | 07004 | |
| Number of page(s) | 4 | |
| Section | Pharmacology | |
| DOI | https://doi.org/10.1051/matecconf/201819707004 | |
| Published online | 12 September 2018 | |
Adverse event of antiepileptic drugs: a cross sectional study
1
Universitas Warmadewa Denpasar, Faculty of Medicine and Health Science, Indonesia
2
Universitas Gadjah Mada Yogyakarta, Faculty of Medicine, Public Health, and Nursing, Indonesia
3
Universitas Gadjah Mada Yogyakarta, Faculty of Pharmacy, Indonesia
4
Wangaya Regional Hospital Denpasar, Department of Neurology, Indonesia
* Corresponding author: nayakasih@gmail.com
Epilepsy is a major non-communicable disorder. Choice between switching to another drug and combining is still debatable when the first antiepileptic drug is ineffective in controlling seizure. Polytherapy usually related with the appearance of adverse effect. This cross sectional study was conducted in Neurology Policlinic with 83 epilepsy patients, consisting of 37 patients used monotherapy and 46 patients used polytherapy. The most common adverse effect was fatigue. Statistical analysis using chi square test showed statistically significant between monotherapy and polytherapy patients against fatigue (p value >0.05). In conclusion, polytherapy is related with the appearance of adverse effect in epilepsy patients.
© The Authors, published by EDP Sciences, 2018
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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