MATEC Web Conf.
Volume 249, 20182018 5th International Conference on Mechanical, Materials and Manufacturing (ICMMM 2018)
|Number of page(s)||5|
|Section||Functional Material Design and Development|
|Published online||10 December 2018|
Improvement of Biological Properties of Natural Hemostatic Agent by Plasma Technology
1 Advanced Technology Research Center (AMTech), Department of Industrial Engineering, Faculty of Engineering, Chiang Mai University, Chiang Mai, Thailand
2 Plasma and Beam Physics Research Facility (PBP), Department of Physics and Materials Science, Faculty of Science, Chiang Mai University, Chiang Mai, 50200, Thailand
3 Biomedical Engineering Institute (BMEI), Chiang Mai University, Chiang Mai, 50200, Thailand
The aim of this study was to evaluate the effect of non-thermal plasma treatment on the biological properties of a natural hemostatic agent. The results show that plasma treatment can enhance the biodegradability property of the hemostatic agent by increasing the degradation rate of the specimen up to 94.26% within 7 days. Furthermore, the plasma-treated specimen also exhibited good biocompatibility based on the cell viability test of the fibroblast cells. The cell growth and cell proliferation on this sample were found to be helpful for the wound healing process. With appropriate degradable and biocompatible properties, this modified agent could be beneficial for better control over bleeding during surgery. Research on the physical and mechanical properties are on to develop novel hemostatic products to match the requirements as far as biomedical applications are concerned.
© The Authors, published by EDP Sciences, 2018
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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