MATEC Web Conf.
Volume 71, 2016The International Conference on Computing and Precision Engineering (ICCPE 2015)
|Number of page(s)||6|
|Section||Modeling, Numerical Simulation and Optimization|
|Published online||02 August 2016|
The Effect of mechanical resistive loading on optimal respiratory signals and breathing patterns under added dead space and CO2 breathing
1 Department of Automatic Control Engineering, Feng Chia University, 40724, Taichung, Taiwan
2 Department of Information Communication, MingDao University, 52345, Changhua, Taiwan
Current study aims to investigate how the respiratory resistive loading affects the behaviour of the optimal chemical-mechanical respiratory control model, the respiratory signals and breathing pattern are optimized under external dead space loading and CO2 breathing. The respiratory control was modelled to include a neuro-muscular drive as the control output to derive the waveshapes of instantaneous airflow, lung volume profiles, and breathing pattern, including total/alveolar ventilation, breathing frequency, tidal volume, inspiratory/expiratory duration, duty cycle, and arterial CO2 pressure. The simulations were performed under various respiratory resistive loads, including no load, inspiratory resistive load, expiratory resistive load, and continuous resistive load. The dead space measurement was described with Gray’s derivation, and simulation results were studied and compared with experimental findings.
© The Authors, published by EDP Sciences, 2016
This is an Open Access article distributed under the terms of the Creative Commons Attribution License 4.0, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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