| Issue |
MATEC Web of Conferences
Volume 4, 2013
ICOMF14 – 14th International Conference on Organized Molecular Films (LB 14)
|
|
|---|---|---|
| Article Number | 05008 | |
| Number of page(s) | 4 | |
| Section | Self-Assembly and Nanoscale Organization | |
| DOI | https://doi.org/10.1051/matecconf/20130405008 | |
| Published online | 13 August 2013 | |
Preparation and characterization of antithrombogenic chitosan/alginate films with enhanced physical stability by cross-linking using layer-by-layer method
1 School of Integrated Design Engineering, Keio University, Yokohama 223-8522, Japan
2 Department of Ceramic Engineering, Kangnung-wonju National University, 123 Jibyeon-dong, Kangwon-do 210-702, Korea
* e-mail: kyong_kyuhong@appi2.appi.keio.ac.jp
We successfully fabricated (chitosan/alginate) (CHI/ALG) multilayer thin film by layer-by-layer (LBL) method. Film durability was enhanced by forming cross-linking using heat treatment, glutaraldehyde, and calcium chloride. Indeed, the adsorption of fibrinogen onto CHI/ALG multilayer thin film was determined by QCM system and it was found that physical stability and protein resistance of CHI/ALG films were improved by cross-linking of the films.
© Owned by the authors, published by EDP Sciences, 2013
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